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Malarone tablets belong to a group of medicines called anti-malarials, containing 2 active ingredients, atovaquone and proguanil hydrochloride. Malarone tablets have the advantage of being used to help prevent malaria, and also help treat malaria. People can become infected with malaria by getting bitten by an infected mosquito, which passes the malaria parasite into the bloodstream. Malarone tablets help to protect against malaria by killing the parasite. For people that are already infected with malaria, Malarone helps to kill the parasites.