Product Description

Atovaquone/Proguanil, more commonly known as generic Malarone is licenced for the prevention of malaria infections in patients travelling to areas of the world where malaria is a problem. Generic drugs like this one are licenced copies of the original brand. Common examples of generics include Ibuprofen -> Nurofen and Paracetamol -> Panadol.

Malaria is typically found in and around the tropics and includes the regions of South America, parts of Asia and sub-Saharan Africa. The burden of malaria is greatest in Africa, but recent developments give hope to the populations who live with this disease.

The combination of Atovaquone and Proguanil is known to be the most effective antimalarial available in the UK, but no anti-malaria medicine is 100% effective. Bite avoidance is the most important line of defence, so you should avoid insect bites by using an appropriate insect repellent.


Generic Malarone tablets should be taken with or after food or a milky drink as follows:


How often should the tablets be taken?1 tablet daily when in the risk area.
When should I start the treatment?2 days before entering the risk area and whilst there.
How long do I take them after leaving the risk area?7 days when leaving the risk area.

Dose: ONE daily starting 2 days before arriving in the malaria risk area, every day whilst there, and then for 7 days after leaving the risk area.

Please note: If you develop flu-like symptoms whilst away or within 1 year of return please see a doctor immediately and explain your travel history.  Many tropical illnesses like malaria often present as a cold or flu-like illness.



Generic Malarone contains the following active ingredients:

Active Ingredients: Atovaquone 250mg and Proguanil 125mg

The following inactive ingredients are also usually found in generic Malarone:

Core: Poloxamer 188, Microcrystalline Cellulose, Low-substituted Hydroxypropyl Cellulose, Povidone K30, Sodium Starch Glycolate Type A, Silica colloidal anhydrous, Magnesium Stearate

Coating: Hypromellose, Titanium Dioxide E171, Iron Oxide Red E172, Macrogol 400, Macrogol 8000


This list is not exhaustive.  For further information please contact us.  


Side Effects

Malarone tablets are usually well tolerated with few side effects. However, about 1 in 10 patients may experience common side effects such as:

  • upset stomach and stomach ache
  • diarrhoea
  • nausea and vomiting
  • headaches

This list of side effects is not exhaustive and for further information, you should read the patient information leaflet.



 This medicine should not be used by patients who:

  • Are allergic to atovaquone or proguanil
  • Suffer from severe kidney impairment (usually defined as chronic kidney disease stage 4)
  • Are pregnant or breastfeeding or intend to be during your trip or two months after, without first seeking specialist advice
  • Have been diagnosed with liver disease or severe kidney disease
  • Weigh less than 40kg


Are currently taking:

  • Warfarin, unless specialist advice has been provided. Warfarin dose adjustments may be required.
  • metoclopramide, used to treat nausea and vomiting
  • the antibiotics, tetracycline, rifampicin, or rifabutin
  • efavirenz or certain highly active protease-inhibitor
  • etoposide


Pregnancy and Breastfeeding

Travel to malaria-endemic regions of the world is not recommended during pregnancy. If you are pregnant we would recommend you do not travel.

Malaria can be dangerous for women who are pregnant. If your trip is unavoidable then please give Travelpharm a call to discuss further.

If you are breastfeeding we will need to speak with you before prescribing this medicine. The makers advise against using it. There is limited information about Atovaquone/Proguanil in breast milk. However, the available data is reassuring.


Always read the patient information leaflet before using this product and if you have any questions please speak with our pharmacist or another medical professional.

Patient Information Leaflet

To view or download this medicine patient information leaflet (PIL) please Click Here

Frequently Asked Questions

How many should I order for my trip?

First of all, check if this product is suitable for your destination. We recommend Travel Health Pro a verified and reliable NHS Travel Resource.

Generic Malarone should be taken daily, starting 1-2 days before travel, whilst at risk and then for 7 days upon leaving. A short holiday of 14 days would need 23 tablets.  

No need to worry about figuring out how many Malarone tablets you need. Our consultation will do that for you when you order them online with us. Clever. You can even add additional family members to your order, saving you time and money on postage.

Where are you based?

We are a UK-registered pharmacy based in Derbyshire. You can check our registration details with the General Pharmaceutical Council on the About Us page. All medicines sold from our pharmacy have been sourced within the UK from MHRA-approved wholesalers. 

My doctor has already written me a prescription for Malarone

Please give us a call so we can advise on the next steps. Using our online consultation is faster, but we understand if you don't want to give us all the information.

One of the team will send you a link. You will need to register online and add the free private prescription product to your basket before checking out.

Please put your prescription in the post and send it to:

Travelpharm, Manor House, Merlin Way, Ilkeston. DE7 4RA with the reference number provided at checkout.

Once we receive your prescription we will calculate the cost and send you a payment link so you can pay online.

Please note that doctors often write prescriptions for the brand Malarone. Whilst Malarone and Atovaquone/Proguanil contain the same active ingredients, Malarone is a brand. Unfortunately, UK law prevents a pharmacy from substituting an unbranded product where a brand has been specified by the prescriber. So if your prescription states Malarone we will only be able to dispense Malarone.

If you require unbranded generic Malarone you will need to get your prescription changed but the original prescriber or simply fill out our online consultation and let our specialist write your prescription.



About us

At Travelpharm we offer FREE delivery on most orders over £35, we aim to provide the best price and service at all times. With genuine products dispensed from our UK pharmacy, we aim to offer a website and service that strives to help you choose the most efficient, suitable medicines for you and your family.

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