Product Description

Maloff Protect tablets are a commonly used medicine used for the prevention of malaria when traveling to areas of the world where malaria is common. 

Maloff has been used for a long time and is now sold without a prescription at local pharmacies like Superdrug, Boots, and Asda, but only in packs of 24 and 36 tablets. What makes us different is that we offer Maloff as individual tablets, so you can buy just the right amount for your trip. Why pay more than you need to?

Malaria is typically found in and around the tropics and this includes the regions of South America, parts of Asia, and sub-Saharan Africa.

The burden of malaria is greatest in Africa, but recent developments give hope to the populations who live with this disease. 


The dosing regimen for malaria prevention in adults 18 years and above is:

How often should the tablets be taken?1 tablet every day with or just after food.
When should I start taking them?2 days before entering the malaria region and whilst there.
How long do I take them after leaving the risk area?7 days (1 week) after leaving the risk area.

Dose: ONE daily starting 2 days before arriving in the malaria risk area, every day whilst there, and then for 7 days after leaving the risk area.

To get the most from Maloff Protect please take with food (preferably a fatty meal) at the same time each day.  

A typical 2-week (14 days) trip will need 23 tablets.

What if I miss a dose?

If you forget to take a dose, don’t worry. Just take your next dose as soon as you remember. Then continue your treatment as before. Don’t take extra tablets to make up for a missed dose. Just take your next dose at the usual time and always ensure you use insect repellents.

Please note: If you develop flu-like symptoms whilst away or within 1 year of return please see a doctor immediately and explain where you have been.


It is important to note that no antimalarials are 100% effective.


Maloff Protect contains the following active ingredients:

Active Ingredients: Atovaquone 250mg and Proguanil 125mg

The following inactive ingredients are also usually found in Maloff:

Core: Poloxamer 188, Microcrystalline Cellulose, Low-substituted Hydroxypropyl Cellulose, Povidone K30, Sodium Starch Glycolate Type A, Silica colloidal anhydrous, Magnesium Stearate

Coating: Hypromellose, Titanium Dioxide E171, Iron Oxide Red E172, Macrogol 400, Polyethylene Glycol 8000


This list is not exhaustive.  For further information please contact us.  

Side Effects

Like all medicines, Maloff Protect Malaria Tablets can cause side effects, although not everybody gets them.

IMPORTANT: If any side effect causes you to stop taking Maloff Protect, or if you vomit or have diarrhoea whilst taking Maloff Protect, you should continue to protect yourself against malaria as much as possible.

Most of the following side effects reported have been mild and have not lasted very long.

Very common: may affect more than 1 in 10 people

  • headache
  • feeling sick and being sick (nausea and vomiting)
  • stomach pain
  • diarrhoea

Common: may affect up to 1 in 10 people

  • dizziness
  • sleeping problems (insomnia)
  • strange dreams
  • depression
  • loss of appetite
  • fever
  • rash
  • cough
  • allergic reactions
  • itching (pruritus)

Common side effects, which may show up in your blood tests are:

  • reduced numbers of red blood cells (anaemia) which can cause tiredness, headaches and shortness of breath
  • reduced numbers of white blood cells (neutropenia) which may make you more likely to catch infections
  • low levels of sodium in the blood (hyponatraemia)
  • an increase in liver enzymes

Uncommon: may affect up to 1 to 100 people

  • anxiety
  • an unusual awareness of the abnormal beating of the heart (palpitations)
  • swelling and redness of the mouth
  • red swollen patches on the skin (hives)
  • hair loss
  • Uncommon side effects that may show up in your blood tests: an increase in amylase (an enzyme produced in the pancreas)

Rare: may affect up to 1 in 1,000 people

  • seeing or hearing things that are not there (hallucinations)

Look out for the following severe reactions. They have occurred in a small number of people, but their exact frequency is unknown.

Stop taking Maloff Protect and contact a doctor immediately if you notice any of the following symptoms:

  • Severe allergic reactions - signs include: rash and itching
  • sudden wheezing, tightness of the chest or throat, or difficulty breathing
  • swollen eyelids, face, lips, tongue or other part of the body
  • Severe skin reactions: skin rash, which may blister and look like small targets (central dark spots, surrounded by a paler area with a dark ring around the edge) (erythema multiforme)
    severe widespread rash with blisters and peeling skin, particularly occurring around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome)



Do not take Maloff Protect if you:

  • are allergic to atovaquone and/or proguanil hydrochloride or any of the ingredients of this medicine
  • have kidney disease
  • have liver disease

Do not take Maloff Protect unless it has been prescribed for you by our team if you:

  • are breastfeeding, pregnant, or think you may be pregnant 
  • are under 18 years old or weigh less than 40 kg
  • have ever had epilepsy, convulsions, or fits
  • suffer from depression
  • have tuberculosis

Do not take Maloff Protect if you are already taking any of the following medicines:

  • etoposide, used to treat cancer
  • metoclopramide, used to treat nausea and vomiting
  • the antibiotics tetracycline, rifampicin, or rifabutin
  • indinavir, efavirenz, zidovudine, or certain medicines called protease inhibitors, used to treat human immunodeficiency virus (HIV)
  • warfarin, other coumarin-based anticoagulants, or new oral anticoagulants (NOACs) such as dabigatran etexilate, rivaroxaban, and apixaban. Talk to your doctor or pharmacist for advice.


Warnings and precautions:

If you are sick (vomit) within one hour of taking your Maloff Protect tablet, take another dose straight away. If you don’t start vomiting until more than one hour after taking Maloff Protect, do not take another Maloff Protect tablet until your next dose is due, as it is likely that Maloff Protect will already be in your system

It is very important to take the full course of Maloff Protect. If you have to take extra tablets due to sickness, you may need to get some more

If you have been vomiting or have diarrhea, it is especially important to use extra bite prevention, such as repellents and bed nets. The Maloff Protect you have taken may not be as effective because you may absorb less than you need.

Tell our pharmacist if you have taken any medicines to prevent or treat malaria before and they have not worked or if you have had an allergic reaction to them. Maloff Protect may not be suitable for you.



Pregnancy and breastfeeding

If you are pregnant, think you may be pregnant or intend to get pregnant, or you are breastfeeding, do not take Maloff Protect unless your specialist tells you to. Pregnant women have an increased risk of developing severe malaria and a higher risk of fatality compared to non-pregnant women.  It is for this reason that we would advise against all but essential travel whilst pregnant.

Seek advice from our pharmacist if you are pregnant or breastfeeding and need to take an antimalarial as we can usually help.


Driving and using machines

Maloff Protect makes some people feel dizzy. If you feel dizzy, do not drive, use machines, or take part in activities where you may put yourself or others at risk.

Patient Information Leaflet

To view or download this medicine patient information leaflet (PIL) please Click Here

Frequently Asked Questions

How many should I order for my trip?

First of all, check if this product is suitable for your destination. We recommend Travel Health Pro a verified and reliable NHS Travel Resource.

Maloff Protect should be taken daily, starting 1-2 days before travel, whilst at risk, and then for 7 days upon leaving. A short holiday of 14 days would need 23 tablets.  

No need to worry about figuring out how many tablets you need. Our consultation will do that for you when you order them online with us. Clever. When you start the consultation you can even add additional family members to your order,  saving you time and money on postage.


Is Maloff the same as Malarone?

Yes, and No.  If you consider the active ingredients alone then the products are identical.  Malarone is made by GlaxoSmithKline and Maloff Protect by Glenmark Pharmaceuticals.  The difference between the two medicines is the UK product license.  

Comparing the two products side by side:

 Maloff ProtectMalarone
Legal CategoryPharmacy Only (P)Prescription Only Medicine (POM)
Available to buy without a prescriptionYesNo
 LicenseMalaria PreventionMalaria Prevention and Treatment
 Ages and Weights 18 years and above 40gk and above (no age restriction)

In essence, despite the medicines containing the same ingredients, there are more restrictions on the sale of Maloff Protect if supplied without a prescription to ensure any risk to the public is managed appropriately.  

We prescribe Maloff Protect using our specialist Pharmacists so are often happy to use this medicine outside of its product license.  Please speak to our team for further information.  



We are a UK-registered pharmacy based in Derbyshire. You can check our registration details with the General Pharmaceutical Council on the About Us page. All medicines sold from our pharmacy have been sourced within the UK from MHRA-approved wholesalers. 




About us

At Travelpharm we offer FREE delivery on most orders over £35, we aim to provide the best price and service at all times. With genuine products dispensed from our UK pharmacy, we aim to offer a website and service that strives to help you choose the most efficient, suitable medicines for you and your family.

Learn about Travelpharm and who we are!
  • GSK Logo - Malarone Tablets
  • Lilly Logo
  • Novartis Logo
  • p&g Logo
  • Roche Logo
  • Teva Logo
Popular Treatments
We've found a few items you may be interested in